Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

AMP-activated protein kinase (AMPK) is an energy sensing metabolic switch in mammalian cells. Here, we report our novel finding that AMPK is lost in all immune cells of experimental autoimmune encephalomyelitis (EAE), an inflammatory disease of Central Nervous System (CNS). AMPKα1 is predominantly e...

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Main Authors: Nath, Narender, Khan, Musfiquidin, Rattan, Ramandeep, Mangalam, Ashutosh, Makkar, Randhir S., de Meester, Carloe, Bertrand, Luc, Singh, Inderjit, Chen, Yingjie, Viollet, Benoit, Giri, Shailendra
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976596/
https://ncbi.nlm.nih.gov/pubmed/19486896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.106
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