5-Aminoimidazole-4-Carboxamide-1-β-4-Ribofuranoside Inhibits Proinflammatory Response in Glial Cells: A Possible Role of AMP-Activated Protein Kinase

AMP-activated protein kinase (AMPK) is tightly regulated by the cellular AMP:ATP ratio and plays a central role in the regulation of energy homeostasis and metabolic stress. A pharmacological activator of AMPK, 5-amino-4-imidazole carboxamide riboside (AICAR) inhibited lipopolysaccharide (LPS)-induc...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Giri, Shailendra, Nath, Narendra, Smith, Brian, Viollet, Benoit, Singh, Avtar K., Singh, Inderjit
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729991/
https://ncbi.nlm.nih.gov/pubmed/14724246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4288-03.2004
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