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5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) Effect on Glucose Production, but Not Energy Metabolism, Is Independent of Hepatic AMPK in Vivo

Metabolic stress, as well as several antidiabetic agents, increases hepatic nucleotide monophosphate (NMP) levels, activates AMP-activated protein kinase (AMPK), and suppresses glucose production. We tested the necessity of hepatic AMPK for the in vivo effects of an acute elevation in NMP on metabol...

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書誌詳細
主要な著者: Hasenour, Clinton M., Ridley, D. Emerson, Hughey, Curtis C., James, Freyja D., Donahue, E. Patrick, Shearer, Jane, Viollet, Benoit, Foretz, Marc, Wasserman, David H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937663/
https://ncbi.nlm.nih.gov/pubmed/24403081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528232
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