Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis

BACKGROUND AND PURPOSE: Glutamate transmission is dysregulated in both multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), the animal model of MS. A characteristic of EAE is increased glutamate transmission associated with up-regulation of AMPA receptors. However, little is...

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Main Authors: Grasselli, G, Rossi, S, Musella, A, Gentile, A, Loizzo, S, Muzio, L, Di Sanza, C, Errico, F, Musumeci, G, Haji, N, Fresegna, D, Sepman, H, De Chiara, V, Furlan, R, Martino, G, Usiello, A, Mandolesi, G, Centonze, D
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Themed Section: Endothelin
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572574/
https://ncbi.nlm.nih.gov/pubmed/22924679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02178.x
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