Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis

BACKGROUND AND PURPOSE: Alterations of glutamate-mediated synaptic transmission occur early during neuroinflammatory insults, and lead to degenerative neuronal damage in multiple sclerosis (MS) and also in experimental autoimmune encephalomyelitis (EAE), which is a murine model of MS. Fingolimod is...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Rossi, S, Lo Giudice, T, De Chiara, V, Musella, A, Studer, V, Motta, C, Bernardi, G, Martino, G, Furlan, R, Martorana, A, Centonze, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
Soggetti:
Research Paper with Commentary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312484/
https://ncbi.nlm.nih.gov/pubmed/21740406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01579.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi