Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis

BACKGROUND AND PURPOSE: Alterations of glutamate-mediated synaptic transmission occur early during neuroinflammatory insults, and lead to degenerative neuronal damage in multiple sclerosis (MS) and also in experimental autoimmune encephalomyelitis (EAE), which is a murine model of MS. Fingolimod is...

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Hlavní autoři: Rossi, S, Lo Giudice, T, De Chiara, V, Musella, A, Studer, V, Motta, C, Bernardi, G, Martino, G, Furlan, R, Martorana, A, Centonze, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Research Paper with Commentary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312484/
https://ncbi.nlm.nih.gov/pubmed/21740406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01579.x
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