Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine

This review covers the last 80 years of remarkable progress in the development of mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first mineralocorticoid to trials of nonsteroidal MRAs. The MR is a nuclear receptor expressed in many tissues/cell types including the kidney, h...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Eur Heart J
Main Authors: Agarwal, Rajiv, Kolkhof, Peter, Bakris, George, Bauersachs, Johann, Haller, Hermann, Wada, Takashi, Zannad, Faiez
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
State of the Art Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813624/
https://ncbi.nlm.nih.gov/pubmed/33099609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehaa736
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