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Suppression of Rapidly Progressive Mouse Glomerulonephritis with the Non-Steroidal Mineralocorticoid Receptor Antagonist BR-4628

BACKGROUND/AIM: Steroidal mineralocorticoid receptor antagonists (MRAs) are effective in the treatment of kidney disease; however, the side effect of hyperkalaemia, particularly in the context of renal impairment, is a major limitation to their clinical use. Recently developed non-steroidal MRAs hav...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ma, Frank Y., Han, Yingjie, Nikolic-Paterson, David J., Kolkhof, Peter, Tesch, Greg H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689384/
https://ncbi.nlm.nih.gov/pubmed/26700873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145666
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