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Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine

This review covers the last 80 years of remarkable progress in the development of mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first mineralocorticoid to trials of nonsteroidal MRAs. The MR is a nuclear receptor expressed in many tissues/cell types including the kidney, h...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Agarwal, Rajiv, Kolkhof, Peter, Bakris, George, Bauersachs, Johann, Haller, Hermann, Wada, Takashi, Zannad, Faiez
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813624/
https://ncbi.nlm.nih.gov/pubmed/33099609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehaa736
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