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30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development

The cDNA of the mineralocorticoid receptor (MR) was cloned 30 years ago, in 1987. At that time, spirolactone, the first generation of synthetic steroid-based MR antagonists (MRAs), which was identified in preclinical in vivo models, had already been in clinical use for 30 years. Subsequent decades o...

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Bibliografiska uppgifter
I publikationen:J Endocrinol
Huvudupphovsmän: Kolkhof, Peter, Bärfacker, Lars
Materialtyp: Artigo
Språk:Inglês
Publicerad: Bioscientifica Ltd 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488394/
https://ncbi.nlm.nih.gov/pubmed/28634268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0600
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