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Myeloid Mineralocorticoid Receptor Activation Contributes to Progressive Kidney Disease

Clinical and experimental studies have shown that mineralocorticoid receptor (MR) antagonists substantially reduce kidney injury. However, the specific cellular targets and mechanisms by which MR antagonists protect against kidney injury must be identified. We used conditional gene deletion of MR si...

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Detalhes bibliográficos
Main Authors: Huang, Louis L., Nikolic-Paterson, David J., Han, Yingjie, Ozols, Elyce, Ma, Frank Y., Young, Morag J., Tesch, Greg H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178428/
https://ncbi.nlm.nih.gov/pubmed/24700867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012111094
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