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Myeloid Mineralocorticoid Receptor Activation Contributes to Progressive Kidney Disease

Clinical and experimental studies have shown that mineralocorticoid receptor (MR) antagonists substantially reduce kidney injury. However, the specific cellular targets and mechanisms by which MR antagonists protect against kidney injury must be identified. We used conditional gene deletion of MR si...

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Autori principali: Huang, Louis L., Nikolic-Paterson, David J., Han, Yingjie, Ozols, Elyce, Ma, Frank Y., Young, Morag J., Tesch, Greg H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178428/
https://ncbi.nlm.nih.gov/pubmed/24700867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012111094
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