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Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis

Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells. Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular Pattern which can promote inflammation during tissue injury. However, the role of CypA in kidney disease is largely unknow...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Leong, Khai Gene, Ozols, Elyce, Kanellis, John, Nikolic-Paterson, David J., Ma, Frank Y.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279441/
https://ncbi.nlm.nih.gov/pubmed/32455976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103667
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