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Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis
Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells. Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular Pattern which can promote inflammation during tissue injury. However, the role of CypA in kidney disease is largely unknow...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7279441/ https://ncbi.nlm.nih.gov/pubmed/32455976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103667 |
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