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22(R)-hydroxycholesterol for dopaminergic neuronal specification of MSCs and amelioration of Parkinsonian symptoms in rats

Oxysterols play vital roles in the human body, ranging from cell cycle regulation and progression to dopaminergic neurogenesis. While naïve human mesenchymal stem cells (hMSCs) have been explored to have neurogenic effect, there is still a grey area to explore their regenerative potential after in v...

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Bibliografski detalji
Izdano u:Cell Death Discov
Glavni autori: Singh, Manisha, Jain, Manish, Bose, Samrat, Halder, Ashutosh, Nag, Tapas Chandra, Dinda, Amit Kumar, Mohanty, Sujata
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811530/
https://ncbi.nlm.nih.gov/pubmed/33454721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-00351-6
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