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22(R)-hydroxycholesterol for dopaminergic neuronal specification of MSCs and amelioration of Parkinsonian symptoms in rats

Oxysterols play vital roles in the human body, ranging from cell cycle regulation and progression to dopaminergic neurogenesis. While naïve human mesenchymal stem cells (hMSCs) have been explored to have neurogenic effect, there is still a grey area to explore their regenerative potential after in v...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Singh, Manisha, Jain, Manish, Bose, Samrat, Halder, Ashutosh, Nag, Tapas Chandra, Dinda, Amit Kumar, Mohanty, Sujata
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811530/
https://ncbi.nlm.nih.gov/pubmed/33454721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-00351-6
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