Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease

Loss of dopaminergic neurons within the substantia nigra (SN) is a pathological hallmark of Parkinsons disease (PD), which leads to the onset of motor symptoms. Previously, our in vitro studies revealed that Angiotensin II (Ang II) induced apoptosis of dopaminergic neurons through its type 1 recepto...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gao, Qing, Ou, Zhou, Jiang, Teng, Tian, You-Yong, Zhou, Jun-Shan, Wu, Liang, Shi, Jian-Quan, Zhang, Ying-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421830/
https://ncbi.nlm.nih.gov/pubmed/28445961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15732
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