Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease

Loss of dopaminergic neurons within the substantia nigra (SN) is a pathological hallmark of Parkinsons disease (PD), which leads to the onset of motor symptoms. Previously, our in vitro studies revealed that Angiotensin II (Ang II) induced apoptosis of dopaminergic neurons through its type 1 recepto...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Gao, Qing, Ou, Zhou, Jiang, Teng, Tian, You-Yong, Zhou, Jun-Shan, Wu, Liang, Shi, Jian-Quan, Zhang, Ying-Dong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper: Gerotarget (Focus on Aging)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421830/
https://ncbi.nlm.nih.gov/pubmed/28445961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15732
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