YAP accelerates vascular senescence via blocking autophagic flux and activating mTOR

Yes‐associated protein (YAP), a major effector of the Hippo signalling pathway, is widely implicated in vascular pathophysiology processes. Here, we identify a new role of YAP in the regulation of vascular senescence. The inhibition or deficiency and overexpression of YAP were performed in human umb...

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Опубликовано в: :J Cell Mol Med
Главные авторы: Pan, Xianmei, Wu, Bo, Fan, Xianglin, Xu, Guanghui, Ou, Caiwen, Chen, Minsheng
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7810949/
https://ncbi.nlm.nih.gov/pubmed/33314583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15902
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