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YAP accelerates vascular senescence via blocking autophagic flux and activating mTOR
Yes‐associated protein (YAP), a major effector of the Hippo signalling pathway, is widely implicated in vascular pathophysiology processes. Here, we identify a new role of YAP in the regulation of vascular senescence. The inhibition or deficiency and overexpression of YAP were performed in human umb...
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| Publicado no: | J Cell Mol Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810949/ https://ncbi.nlm.nih.gov/pubmed/33314583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15902 |
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