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Inhibition of MTOR Disrupts Autophagic Flux in Podocytes

Inhibitors of the mammalian target of rapamycin (MTOR) belong to a family of drugs with potent immunosuppressive, antiangiogenic, and antiproliferative properties. De novo or worsening proteinuria can occur during treatment with these agents, but the mechanism by which this occurs is unknown. We gen...

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書誌詳細
主要な著者: Cinà, Davide P., Onay, Tuncer, Paltoo, Aarti, Li, Chengjin, Maezawa, Yoshiro, De Arteaga, Javier, Jurisicova, Andrea, Quaggin, Susan E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294311/
https://ncbi.nlm.nih.gov/pubmed/22193387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011070690
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