Loss of the Podocyte-Expressed Transcription Factor Tcf21/Pod1 Results in Podocyte Differentiation Defects and FSGS

Podocytes are terminally differentiated cells with an elaborate cytoskeleton and are critical components of the glomerular barrier. We identified a bHLH transcription factor, Tcf21, that is highly expressed in developing and mature podocytes. Because conventional Tcf21 knockout mice die in the perin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Maezawa, Yoshiro, Onay, Tuncer, Scott, Rizaldy P., Keir, Lindsay S., Dimke, Henrik, Li, Chengjin, Eremina, Vera, Maezawa, Yuko, Jeansson, Marie, Shan, Jingdong, Binnie, Matthew, Lewin, Moshe, Ghosh, Asish, Miner, Jeffrey H., Vainio, Seppo J., Quaggin, Susan E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2014
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214535/
https://ncbi.nlm.nih.gov/pubmed/24904088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121307
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