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Cadmium Exposure Activates Akt/ERK Signaling and Pro-Inflammatory COX-2 Expression in Human Gallbladder Epithelial Cells via a ROS Dependent Mechanism.
Gallbladder cancer (GBC) is the commonest biliary tract cancer with an ill-defined etiology. We examined the role of Cd(+2) exposures in a primary human gallbladder (GB) cell line model in this study. Cd(+2) exposures induced decreased cell viability, reactive oxygen species (ROS) generation, altere...
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| Publicado no: | Toxicol In Vitro |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809918/ https://ncbi.nlm.nih.gov/pubmed/32512147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2020.104912 |
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