Role of the PI3K/Akt pathway in cadmium induced malignant transformation of normal prostate epithelial cells.

This study investigated the role of the PI3K/Akt pathway in cadmium (Cd) induced malignant transformation of normal prostate epithelial (PWR1E and RWPE1) cells. Both PWR1E and RWPE1 cells were exposed to 10μM Cd for one year and designated as Cd-PWR1E and Cd-RWPE1. Cd-RWPE1 cells robustly formed tum...

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Enregistré dans:
Détails bibliographiques
Publié dans:Toxicol Appl Pharmacol
Auteurs principaux: Kulkarni, Priyanka, Dasgupta, Pritha, Bhat, Nadeem S, Hashimoto, Yutaka, Saini, Sharanjot, Shahryari, Varahram, Yamamura, Soichiro, Shiina, Marisa, Tanaka, Yuichiro, Dahiya, Rajvir, Majid, Shahana
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726053/
https://ncbi.nlm.nih.gov/pubmed/33129824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115308
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