Role of the PI3K/Akt pathway in cadmium induced malignant transformation of normal prostate epithelial cells.

This study investigated the role of the PI3K/Akt pathway in cadmium (Cd) induced malignant transformation of normal prostate epithelial (PWR1E and RWPE1) cells. Both PWR1E and RWPE1 cells were exposed to 10μM Cd for one year and designated as Cd-PWR1E and Cd-RWPE1. Cd-RWPE1 cells robustly formed tum...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Kulkarni, Priyanka, Dasgupta, Pritha, Bhat, Nadeem S, Hashimoto, Yutaka, Saini, Sharanjot, Shahryari, Varahram, Yamamura, Soichiro, Shiina, Marisa, Tanaka, Yuichiro, Dahiya, Rajvir, Majid, Shahana
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726053/
https://ncbi.nlm.nih.gov/pubmed/33129824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115308
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