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Inactive variants of death receptor p75(NTR) reduce Alzheimer’s neuropathology by interfering with APP internalization
A prevalent model of Alzheimer’s disease (AD) pathogenesis postulates the generation of neurotoxic fragments derived from the amyloid precursor protein (APP) after its internalization to endocytic compartments. The molecular pathways that regulate APP internalization and intracellular trafficking in...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | EMBO J |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809794/ https://ncbi.nlm.nih.gov/pubmed/33258176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104450 |
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