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Inactive variants of death receptor p75(NTR) reduce Alzheimer’s neuropathology by interfering with APP internalization
A prevalent model of Alzheimer’s disease (AD) pathogenesis postulates the generation of neurotoxic fragments derived from the amyloid precursor protein (APP) after its internalization to endocytic compartments. The molecular pathways that regulate APP internalization and intracellular trafficking in...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809794/ https://ncbi.nlm.nih.gov/pubmed/33258176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104450 |
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