SPIN reveals genome-wide landscape of nuclear compartmentalization

We report SPIN, an integrative computational method to reveal genome-wide intranuclear chromosome positioning and nuclear compartmentalization relative to multiple nuclear structures, which are pivotal for modulating genome function. As a proof-of-principle, we use SPIN to integrate nuclear compartm...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Wang, Yuchuan, Zhang, Yang, Zhang, Ruochi, van Schaik, Tom, Zhang, Liguo, Sasaki, Takayo, Peric-Hupkes, Daniel, Chen, Yu, Gilbert, David M., van Steensel, Bas, Belmont, Andrew S., Ma, Jian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809771/
https://ncbi.nlm.nih.gov/pubmed/33446254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02253-3
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