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Local rewiring of genome–nuclear lamina interactions by transcription

Transcriptionally inactive genes are often positioned at the nuclear lamina (NL), as part of large lamina‐associated domains (LADs). Activation of such genes is often accompanied by repositioning toward the nuclear interior. How this process works and how it impacts flanking chromosomal regions are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Brueckner, Laura, Zhao, Peiyao A, van Schaik, Tom, Leemans, Christ, Sima, Jiao, Peric‐Hupkes, Daniel, Gilbert, David M, van Steensel, Bas
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073462/
https://ncbi.nlm.nih.gov/pubmed/32080885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103159
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