Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence

In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...

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Detalhes bibliográficos
Main Authors: Meuleman, Wouter, Peric-Hupkes, Daan, Kind, Jop, Beaudry, Jean-Bernard, Pagie, Ludo, Kellis, Manolis, Reinders, Marcel, Wessels, Lodewyk, van Steensel, Bas
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561868/
https://ncbi.nlm.nih.gov/pubmed/23124521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.141028.112
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