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Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases
Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively little is known about how most preferences are encoded in the...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809594/ https://ncbi.nlm.nih.gov/pubmed/33440154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108602 |
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