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Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability
Cell survival is regulated by a signaling network driven by the activity of protein kinases; however, determining the contribution that each kinase in the network makes to such regulation remains challenging. Here, we report a computational approach that uses mass spectrometry-based phosphoproteomic...
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Publicado no: | Mol Cell Proteomics |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587867/ https://ncbi.nlm.nih.gov/pubmed/28674151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O116.064360 |
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