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Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

Mass spectrometry is widely used to probe the proteome and its modifications in an untargeted manner, with unrivalled coverage. Applied to phosphoproteomics, it has tremendous potential to interrogate phospho-signalling and its therapeutic implications. However, this task is complicated by issues of...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Terfve, Camille D. A., Wilkes, Edmund H., Casado, Pedro, Cutillas, Pedro R., Saez-Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579397/
https://ncbi.nlm.nih.gov/pubmed/26354681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9033
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