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Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability

Cell survival is regulated by a signaling network driven by the activity of protein kinases; however, determining the contribution that each kinase in the network makes to such regulation remains challenging. Here, we report a computational approach that uses mass spectrometry-based phosphoproteomic...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Proteomics
Päätekijät: Wilkes, Edmund H., Casado, Pedro, Rajeeve, Vinothini, Cutillas, Pedro R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Biochemistry and Molecular Biology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587867/
https://ncbi.nlm.nih.gov/pubmed/28674151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O116.064360
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