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Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand

The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2, making evaluation of its activity in vivo diffic...

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Dades bibliogràfiques
Publicat a:ACS Chem Biol
Autors principals: Koch, Peter David, Ahmed, Maaz S., Kohler, Rainer H., Li, Ran, Weissleder, Ralph
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808335/
https://ncbi.nlm.nih.gov/pubmed/31809013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00724
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