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Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand

The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2, making evaluation of its activity in vivo diffic...

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Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Koch, Peter David, Ahmed, Maaz S., Kohler, Rainer H., Li, Ran, Weissleder, Ralph
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808335/
https://ncbi.nlm.nih.gov/pubmed/31809013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00724
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