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Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand
The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2, making evaluation of its activity in vivo diffic...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808335/ https://ncbi.nlm.nih.gov/pubmed/31809013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00724 |
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