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Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand

The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2, making evaluation of its activity in vivo diffic...

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Podrobná bibliografie
Vydáno v:ACS Chem Biol
Hlavní autoři: Koch, Peter David, Ahmed, Maaz S., Kohler, Rainer H., Li, Ran, Weissleder, Ralph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808335/
https://ncbi.nlm.nih.gov/pubmed/31809013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00724
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