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Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand

The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2, making evaluation of its activity in vivo diffic...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Principais autores: Koch, Peter David, Ahmed, Maaz S., Kohler, Rainer H., Li, Ran, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808335/
https://ncbi.nlm.nih.gov/pubmed/31809013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00724
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