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SMALL MOLECULE IMAGING AGENT FOR MUTANT KRAS G12C
Multiple potent covalent inhibitors for mutant KRAS G12C have been described and some are in clinical trials. These small molecule inhibitors potentially allow for companion imaging probe development, thereby expanding the chemical biology toolkit to investigate mutant KRAS biology. Herein, we synth...
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| Vydáno v: | Adv Ther (Weinh) |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115719/ https://ncbi.nlm.nih.gov/pubmed/33997272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.202000290 |
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