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High expression of hypoxia inducible factor 1α related with acquired resistant to EGFR tyrosine kinase inhibitors in NSCLC

The acquired resistance of the first generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is a main factor leading to poor prognosis of non-small cell lung cancer (NSCLC), so we researched whether the high expression of hypoxia-inducible factor-1α (HIF-1α) in EGFR-TKIs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jin, Qian, Huang, Feihua, Xu, Xianrong, He, Haidong, Zhang, Yingqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806909/
https://ncbi.nlm.nih.gov/pubmed/33441708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79801-1
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