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Management of acquired resistance to EGFR kinase inhibitors in advanced NSCLC

The widespread adoption of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for the first-line treatment of advanced EGFR-mutated non-small cell lung cancer (NSCLC) has resulted in acquired TKI resistance becoming a ubiquitous clinical problem. The identification of specific...

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Detalles Bibliográficos
Main Authors: Sacher, Adrian G., Jänne, Pasi A., Oxnard, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117471/
https://ncbi.nlm.nih.gov/pubmed/24752335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28723
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