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Modeling the Binding Mechanism of Remdesivir, Favilavir, and Ribavirin to SARS-CoV-2 RNA-Dependent RNA Polymerase
[Image: see text] Recent efforts to repurpose drugs to combat COVID-19 have identified Remdesivir as a candidate. It acts on the RNA-dependent, RNA polymerase (RdRp) of the SARS-CoV-2 virus, a protein complex responsible for mediating replication of the virus’s genome. However, its exact action mech...
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| Udgivet i: | ACS Cent Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2021
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7805600/ https://ncbi.nlm.nih.gov/pubmed/33527086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c01242 |
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