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A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate

BACKGROUND: The bacterial GlgE pathway is the third known route to glycogen and is the only one present in mycobacteria. It contributes to the virulence of Mycobacterium tuberculosis. The involvement of GlgE in glycogen biosynthesis was discovered twenty years ago when the phenotype of a temperature...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta Gen Subj
Main Authors: Syson, Karl, Batey, Sibyl F.D., Schindler, Steffen, Kalscheuer, Rainer, Bornemann, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805345/
https://ncbi.nlm.nih.gov/pubmed/33166604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129783
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