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A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate

BACKGROUND: The bacterial GlgE pathway is the third known route to glycogen and is the only one present in mycobacteria. It contributes to the virulence of Mycobacterium tuberculosis. The involvement of GlgE in glycogen biosynthesis was discovered twenty years ago when the phenotype of a temperature...

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Dettagli Bibliografici
Pubblicato in:Biochim Biophys Acta Gen Subj
Autori principali: Syson, Karl, Batey, Sibyl F.D., Schindler, Steffen, Kalscheuer, Rainer, Bornemann, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805345/
https://ncbi.nlm.nih.gov/pubmed/33166604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2020.129783
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