Ultra-purified alginate gel implantation decreases inflammatory cytokine levels, prevents intervertebral disc degeneration, and reduces acute pain after discectomy

Lumbar intervertebral disc (IVD) herniation causes severe low back pain (LBP), which results in substantial financial and emotional strains. Despite the effectiveness of discectomy, there is no existing treatment for post-operative LBP induced by progressive IVD degeneration. Two key factors of LBP...

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Vydáno v:Sci Rep
Hlavní autoři: Ura, Katsuro, Yamada, Katsuhisa, Tsujimoto, Takeru, Ukeba, Daisuke, Iwasaki, Norimasa, Sudo, Hideki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804289/
https://ncbi.nlm.nih.gov/pubmed/33436742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79958-9
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