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Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis

Accumulating evidence shows that RAGE has an important function in the pathogenesis of sepsis. However, the mechanisms by which RAGE transduces signals to downstream kinase cascades during septic shock are not clear. Here, we identify SLP76 as a binding partner for the cytosolic tail of RAGE both in...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Yan, Zhengzheng, Luo, Haihua, Xie, Bingyao, Tian, Tian, Li, Shan, Chen, Zhixia, Liu, Jinghua, Zhao, Xuwen, Zhang, Liyong, Deng, Yongqiang, Billiar, Timothy R., Jiang, Yong
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804203/
https://ncbi.nlm.nih.gov/pubmed/33436632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20577-3
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