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The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation

T cell responses are critical to the survival of Yersinia-infected animals. Yersinia have the ability to directly suppress T lymphocyte activation through the virulence factor YopH, a tyrosine phosphatase. Using single cell video microscopy and FACS analysis, here we show that even an average of one...

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Detalhes bibliográficos
Main Authors: Gerke, Christiane, Falkow, Stanley, Chien, Yueh-hsiu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213036/
https://ncbi.nlm.nih.gov/pubmed/15699071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041120
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