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Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose

While numerous techniques can be used to measure and analyze insulin secretion in isolated islets in culture, assessments of insulin secretion in vivo are typically indirect and only semiquantitative. The CpepSfGFP reporter mouse line allows the in vivo imaging of insulin secretion from individual i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Frikke-Schmidt, Henriette, Arvan, Peter, Seeley, Randy J., Cras-Méneur, Corentin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804140/
https://ncbi.nlm.nih.gov/pubmed/33436691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79727-8
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