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Heterogeneity and compartmental properties of insulin storage and secretion in rat islets.

To investigate compartmental properties of insulin storage and secretion, isolated rat islets were used for pulse-labeling experiments, after which proinsulin and insulin were purified rigorously. Processing of proinsulin to insulin neared completion by 3 h without additional loss of either radioact...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Gold, G, Landahl, H D, Gishizky, M L, Grodsky, G M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7037852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110481
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