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Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity
The pathogenesis of ulcerative colitis (UC), a major type of inflammatory bowel disease, remains unknown. No model exists that adequately recapitulates the complexity of clinical UC. Here, we take advantage of induced pluripotent stem cells (iPSCs) to develop an induced human UC-derived organoid (iH...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801686/ https://ncbi.nlm.nih.gov/pubmed/33431859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20351-5 |
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