Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids

Ulcerative colitis (UC) is a prevalent form of inflammatory bowel disease (IBD) whose pathogenic mechanisms remain unclear. Elucidating these mechanisms is important to reduce UC symptoms and to prevent UC progression into colitis-associated colon cancer (CAC). Our goal was to develop and validate f...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Sarvestani, Samaneh K., Signs, Steven A., Lefebvre, Veronique, Mack, Stephen, Ni, Ying, Morton, Andrew, Chan, Ernest R., Li, Xiaoxia, Fox, Paul, Ting, Angela, Kalady, Matthew F., Cruise, Michael, Ashburn, Jean, Stiene, Jennifer, Lai, Wei, Liska, David, Xiang, Shao, Huang, Emina H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2018
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033374/
https://ncbi.nlm.nih.gov/pubmed/29983891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25617
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