Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids

Ulcerative colitis (UC) is a prevalent form of inflammatory bowel disease (IBD) whose pathogenic mechanisms remain unclear. Elucidating these mechanisms is important to reduce UC symptoms and to prevent UC progression into colitis-associated colon cancer (CAC). Our goal was to develop and validate f...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sarvestani, Samaneh K., Signs, Steven A., Lefebvre, Veronique, Mack, Stephen, Ni, Ying, Morton, Andrew, Chan, Ernest R., Li, Xiaoxia, Fox, Paul, Ting, Angela, Kalady, Matthew F., Cruise, Michael, Ashburn, Jean, Stiene, Jennifer, Lai, Wei, Liska, David, Xiang, Shao, Huang, Emina H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033374/
https://ncbi.nlm.nih.gov/pubmed/29983891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25617
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