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Cancer associated talin point mutations disorganise cell adhesion and migration
Talin-1 is a key component of the multiprotein adhesion complexes which mediate cell migration, adhesion and integrin signalling and has been linked to cancer in several studies. We analysed talin-1 mutations reported in the Catalogue of Somatic Mutations in Cancer database and developed a bioinform...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801617/ https://ncbi.nlm.nih.gov/pubmed/33431906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77911-4 |
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