Mechanical stability of talin rod controls cell migration and substrate sensing

Cells adhere to the surrounding tissue and probe its mechanical properties by forming cell-matrix adhesions. Talin is a critical adhesion protein and participates in the transmission of mechanical signals between extracellular matrix and cell cytoskeleton. Force induced unfolding of talin rod subdom...

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Publicado en:Sci Rep
Main Authors: Rahikainen, Rolle, von Essen, Magdaléna, Schaefer, Markus, Qi, Lei, Azizi, Latifeh, Kelly, Conor, Ihalainen, Teemu O., Wehrle-Haller, Bernhard, Bastmeyer, Martin, Huang, Cai, Hytönen, Vesa P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472591/
https://ncbi.nlm.nih.gov/pubmed/28620171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03335-2
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