Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing

Integrin-dependent cell adhesion and spreading are critical for morphogenesis, tissue regeneration, and immune defense but also tumor growth. However, the mechanisms that induce integrin-mediated cell spreading and provide mechanosensing on different extracellular matrix conditions are not fully und...

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Detalhes bibliográficos
Main Authors: Pinon, Perrine, Pärssinen, Jenita, Vazquez, Patricia, Bachmann, Michael, Rahikainen, Rolle, Jacquier, Marie-Claude, Azizi, Latifeh, Määttä, Juha A., Bastmeyer, Martin, Hytönen, Vesa P., Wehrle-Haller, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003243/
https://ncbi.nlm.nih.gov/pubmed/24778313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201308136
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