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New PI(4,5)P(2)- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering

Integrin-dependent adhesion sites consist of clustered integrins that transmit mechanical forces and provide signaling required for cell survival and morphogenesis. Despite their importance, the regulation of integrin clustering by the cytoplasmic adapter protein talin (Tal) and phosphatidylinositol...

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Detalhes bibliográficos
Main Authors: Saltel, Frédéric, Mortier, Eva, Hytönen, Vesa P., Jacquier, Marie-Claude, Zimmermann, Pascale, Vogel, Viola, Liu, Wei, Wehrle-Haller, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806581/
https://ncbi.nlm.nih.gov/pubmed/19948488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908134
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