Mechanotransduction in talin through the interaction of the R8 domain with DLC1

The mechanical unfolding of proteins is a cellular mechanism for force transduction with potentially broad implications in cell fate. Despite this, the mechanism by which protein unfolding elicits differential downstream signalling pathways remains poorly understood. Here, we used protein engineerin...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Haining, Alexander William M., Rahikainen, Rolle, Cortes, Ernesto, Lachowski, Dariusz, Rice, Alistair, von Essen, Magdalena, Hytönen, Vesa P., del Río Hernández, Armando
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Short Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054372/
https://ncbi.nlm.nih.gov/pubmed/30028837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005599
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