Mechanotransduction in talin through the interaction of the R8 domain with DLC1

The mechanical unfolding of proteins is a cellular mechanism for force transduction with potentially broad implications in cell fate. Despite this, the mechanism by which protein unfolding elicits differential downstream signalling pathways remains poorly understood. Here, we used protein engineerin...

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Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Haining, Alexander William M., Rahikainen, Rolle, Cortes, Ernesto, Lachowski, Dariusz, Rice, Alistair, von Essen, Magdalena, Hytönen, Vesa P., del Río Hernández, Armando
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Short Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054372/
https://ncbi.nlm.nih.gov/pubmed/30028837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005599
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