Mechanotransduction in talin through the interaction of the R8 domain with DLC1

The mechanical unfolding of proteins is a cellular mechanism for force transduction with potentially broad implications in cell fate. Despite this, the mechanism by which protein unfolding elicits differential downstream signalling pathways remains poorly understood. Here, we used protein engineerin...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Haining, Alexander William M., Rahikainen, Rolle, Cortes, Ernesto, Lachowski, Dariusz, Rice, Alistair, von Essen, Magdalena, Hytönen, Vesa P., del Río Hernández, Armando
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054372/
https://ncbi.nlm.nih.gov/pubmed/30028837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005599
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